- A kind of mental unsoundness characterized by extreme
depression of spirits, ill-grounded fears, delusions, and brooding over
one particular subject or train of ideas.
Melancholia Melancholia is a pathological extent of a melancholy mood, characterized by sadness and severe depression.
Involutional melancholia Involutional melancholia is a state of depression and anxiety associated traditionally with the menopause and with mid-life crises in general.